Powering Singapore Health Discovery
Lifebit turns Multi-Modal Data Complexity into Insights Actionable Precision Medicine
Building the federated platform behind TRUST — Singapore’s Trusted Research and Real-World Data Discovery and Utilisation Platform — with Synapxe, the national HealthTech agency.
“Through our collaboration with Lifebit, we are advancing the use of research and clinical insights using clinico-genomic data for precision medicine. By doing so, we hope to accelerate the translation into clinical workflows, in a manner that will make a significant impact to improving healthcare for Singaporeans.”
Andy Ta
Chief Data Officer and Director, Data Analytics & AI of Synapxe
Challenges
- 20PB of genomic and linked health data, making data transfer and duplication impractical
- High PDPA and MOH security requirements to access sensitive genomic and clinical datasets
- Need to scalably support 1000+ researchers and multiple external partners (including pharma)
- High complexity of securely linking multi-modal datasets (genomics, EHR, registries, imaging, lifestyle)
Outcomes
- Federated, privacy-preserving analysis without moving sensitive data
- Secure data linkage across genomic, clinical, registry, and longitudinal datasets
- Accelerated precision medicine for Asian populations, with faster translation to clinical and population health impact
- Improved biomarker discovery and patient stratification across population-scale cohorts
- Enablement of public-private partnerships between healthcare, academia, and pharma
impact
100,000
Singaporean participants
20% Malay, 20% Indian, 60% Chinese
20
Petabytes
of data
37
Research
projects launched
7
Global
pharmaceutical companies engaged
100%
Adherence
to Singapore Gov. security & regulatory requirements
FAQs
A federated platform for clinico-genomic precision medicine
Sovereign by architecture
Data, compute, and audit logs remain inside Singapore. There is no architectural path by which patient-level data leaves the perimeter, regardless of researcher accreditation.
Linked clinical + genomic analytics
Researchers can ask questions that require both clinical and genomic context in a single analytic environment, supporting precision-medicine programmes that would otherwise require multi-site data movement.
Operational governance under Synapxe
Project approvals, accreditation, data-use agreements, and audit trails are run by Synapxe and the Ministry of Health — not by a foreign vendor. The platform is the analytics layer; control of the platform stays in Singapore.
A research toolkit, not a black box
Jupyter, R, Nextflow, and Lifebit’s federated AI tooling all run inside the environment, so researchers use the tools they already know without exporting data to use them.
Next step
Want a sovereign TRE for your country?
Lifebit’s federated platform is deployed for national health data programmes from the UK to Singapore — with data, compute, and governance staying in-country.