Powering Health Non-Profits

Lifebit turns Costly Research Barriers into Accessible Scientific Discovery
Supporting the Lupus Research Alliance’s DREAM platform — uniting molecular and clinico-phenotypic data across 9+ CROs in the US and Canada, so every researcher can analyse the full cohort without the data ever leaving its governed environment.
“If any research organisation is looking to make the most of their data management and have the impact within their community, connecting with the Lifebit team is a must.”
Grant Roesler
DREAM Platform Administrator, Lupus Research Alliance

Challenges
- Strict trans-national privacy and governance requirements
- High cost and risk of transferring datasets
- Ensuring adherence to data access agreements across multiple jurisdictions
- Harmonising distributed molecular and clinico-phenotypic datasets from 9+ CROs
- Costly cloud analyses limiting researchers’ ability to run all required studies
Outcomes
- A flexible data management infrastructure that grows as the cohort and data types grow
- From Excel to the command line — analytical tooling that caters to every user skill level
- Standardised data assets promote findability and usability of diverse molecular and clinico-phenotypic data
- Support every step of the way — guided training sessions to ensure clinicians and researchers alike can deliver results for their patients
- 30–90% lower cloud costs through large-scale analysis optimisation
impact
100%
OMOP mapping
coverage of molecular and clinico-phenotypic data
3
Clinical sites
onboarded to the DREAM platform
100%
Adherence
to US and Canadian data governance requirements
30–90%
Lower cloud costs
through large-scale analysis optimisation
FAQs
A research platform built for non-profit lupus discovery
Lifebit’s federated platform underpins the Lupus Research Alliance’s DREAM environment. Researchers across 9+ CROs analyse harmonised molecular and clinico-phenotypic data inside one shared, governed workspace — without the cost or risk of moving sensitive datasets between sites.
What the DREAM platform delivers:
Harmonised data across the lupus research network
Distributed molecular and clinico-phenotypic data from 9+ CROs are mapped to OMOP and made queryable through one consistent layer — researchers can ask the same question across cohorts without rebuilding the data each time.
Tooling for every skill level
DREAM spans spreadsheet-style exploration, point-and-click analysis, and full Jupyter and RStudio environments. Clinicians, statisticians, and computational researchers each work in the interface that fits their workflow, against the same governed dataset.
Cross-border governance, automatically enforced
US and Canadian data access agreements, Five Safes principles, and project-level approvals are enforced consistently across every researcher session — removing the manual burden of tracking compliance per dataset.
Lower cost, broader access
Large-scale analysis optimisation cuts cloud spend by 30–90%, freeing budget that the Lupus Research Alliance reinvests into research capacity rather than infrastructure.
Next step
Ready to see this in your environment?
Lifebit’s federated platform powers research at Genomics England, the NIH, Boehringer Ingelheim, the Lupus Research Alliance, and beyond. Yours could be next.
