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70 articles · page 1 of 6
Genomics data sharing is still broken in 2026 because the entire system still assumes data must move to be analyzed. Data Transfer Agreements take…
Data Transfer Agreements take 18–36 months because they attempt to reconcile three fundamentally opposing forces at once: institutional risk…
An agentic federated Trusted Research Environment (TRE) is a research platform in which artificial intelligence (AI) agents carry out analytical work…
A federated Trusted Research Environment (TRE) reference architecture for a national genomics program keeps every genome and health record inside the…
Combining the Observational Medical Outcomes Partnership Common Data Model (OMOP CDM) with a federated Trusted Research Environment (TRE) solves two…
Standing up a national Trusted Research Environment (TRE) is not a binary build-versus-buy decision: the programs that work treat the governance…
A data clean room is a neutral computing environment — originating in advertising technology — where two or more parties match and analyze their…
Output checking is the process of reviewing every result a researcher wants to take out of a Trusted Research Environment (TRE) — tables, figures…
A Data Access Committee (DAC) is the governance body that reviews and decides applications from researchers who want to use a sensitive dataset…
Centralized data governance copies datasets into a single repository, making harmonization easy but creating regulatory, security and scalability…
The Five Safes framework is the canonical model for governing research access to sensitive data, comprising Safe People, Safe Projects, Safe…
An automated airlock is the disclosure-control gate at the boundary of a Trusted Research Environment (TRE) that reviews every output before it…
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